SINGLE-CELL RNA-SEQ REVEALS CHARACTERISTICS OF MALIGNANT CELLS AND IMMUNE MICROENVIRONMENT IN SUBCUTANEOUS PANNICULITIS-LIKE T-CELL LYMPHOMA

Single-Cell RNA-seq Reveals Characteristics of Malignant Cells and Immune Microenvironment in Subcutaneous Panniculitis-Like T-Cell Lymphoma

BackgroundSubcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a malignant primary T-cell lymphoma that is challenging to distinguish from autoimmune disorders and reactive panniculitides.Delay in diagnosis and a high misdiagnosis rate affect the prognosis and survival of patients.The difficulty of diagnosis is mainly due to an incomplete unde

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New Quinolone-Based Thiosemicarbazones Showing Activity Against Plasmodium falciparum and Mycobacterium tuberculosis

Co-infection of malaria and tuberculosis, although not thoroughly investigated, has been noted.With the increasing prevalence of tuberculosis in the African region, wherein trailmaster challenger 200x malaria is endemic, it is intuitive to suggest that the probability of co-infection with these diseases is likely to increase.To avoid the issue of d

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